HGH and Bodybuilding
Human growth hormone is an anabolic hormone, which means that it takes part in the process of building muscles and other body tissues except the brain. HGH works by interacting with a unique receptor on the surface of cells. This is a general principle of work of all protein hormones.
Human growth hormone affects the process of body growth in two ways. As polypeptide hormones aren't fat-soluble, they aren't able to penetrate sarcolemma. So, human growth hormones bind to receptors on target cells, activating a second messenger. Due to this mechanism GH stimulates multiplication and division of chondrocytes of cartilage and muscle cells.
Human growth hormone stimulates the release of insulin-like growth factor 1. The latter is a hormone similar to proinsulin. It is produced by the liver which is the principal site of IGF-1 production. IGF-1 makes cells and tissues grow, as well as promotes bone growth by affecting the work of osteoblast and chondrocyte.
Due to these mechanisms, the effect of human growth hormone is expressed in building muscles, bones and tissues, simultaneously burning fat. It significantly improves athletic performance by converting fat to energy. It becomes clear how HGH builds muscle and burns fat at the same time.